Fig. 1

Spatial characteristics pertaining to distinct cell types within BPH tissue. A H&E staining of tissue section (left) and mapped with unbiased clustering of ST spots in BPH sample (right). Each cluster is labeled in different color. Scale bar = 1 mm. B UMAP plot of 2945 ST spots from a BPH ST data. Each cluster is shown in different color. (C) Weight of each cell type in a BPH tissue slide determined using RCTD. D Scatterpies of weights for different cell types in a spot in ST data. E Heatmap displaying the weight of each cell type for Seurat clusters in ST data. F ST spots of nodules, cluster1 (C1), cluster2 (C2), cluster3 (C3), and cluster5 (C5) in the BPH sample, each distinctly labeled in different colors