The redox-active defensive Selenoprotein T as a novel stress sensor protein playing a key role in the pathophysiology of heart failure

Table 2 Basal cardiac parameters after stabilization

Experimental group	dLVP (mmHg)	LVEDP (mmHg)	+ (LVdP/dt)_max (mmHg/s)	−(LVdP/dt)_max (mmHg/s)	HR (beats/min)	CP (mmHg)
WST	87 ± 12	6 ± 1	2813 ± 191	− 1944 ± 154	247 ± 8	68 ± 1
WST + PSELT	106 ± 12	7 ± 1	3091 ± 138	− 2121 ± 62	238 ± 5	68 ± 2
SHHF	56 ± 4^*	8 ± 1	2128 ± 121^**	− 1580 ± 75^*	256 ± 11	107 ± 2^***
SHHF + PSELT	88 ± 5^†	7 ± 1	2547 ± 93^†	− 1873 ± 68^†	250 ± 4	86 ± 2^†††

dLVP: developed left ventricular pressure; LVEDP: left ventricular end-diastolic pressure; + (LVdP/dt)_max: maximal rate of left ventricular contraction; -(LVdP/dt)_max: maximal rate of left ventricular pressure decline; HR: heart rate; CP: coronary pressure
Basal cardiac parameters after stabilization. n = 6 for each experimental group; data are expressed as means ± SEM; ^*p < 0.05; ^**p < 0.01; ^***p < 0.001 WST vs SHHF; ^†p < 0.05; ^†††p < 0.001 SHHF vs SHHF + PSELT
Statistical significance: One-way ANOVA and the non-parametric Newman-Keuls Multiple Comparison Test

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