Table 3 Summary of the drug encapsulated, kind of application, production technique and characteristics of niosomes obtained in the different works described
NIOSOMES | ||||||
|---|---|---|---|---|---|---|
Encapsulated drug | Application | Production technique | Type of surfactant | Size [nm] | ζ-potential [mV] | Ref. |
DNA | Hepatitis B vaccine | Reverse phase evaporation | Span 85 | 2300 | - | [93] |
Influenza antigen | Vaccine | Thin film hydration/microfluidic | Monopalmitin, dicetyl phosphate | 388–122 | From − 14 to -28 | [94] |
Toxoplasma lysate antigen | Inflammatory arthritis | Thin film hydration | Span 60 | 164 | -57 | [96] |
Plasmid DNA-encoding ovalbumin | Skin immunization via microneedles | Thin film hydration | Span 20, N1, N1-dimyristeroyloxyethyl-spermine | 400–600 | - | [98] |