TRANSFERSOMES | ||||||
---|---|---|---|---|---|---|
Encapsulated drug | Application | Production technique | Type of lipid/surfactant | Size [nm] | ζ-potential [mV] | Ref. |
Tetanus-toxoid | Topical immunization | Thin film hydration | PC, sodium deoxycholate | 172–195 | - | [83] |
Plasmid DNA | Hepatitis B vaccines | Reverse phase evaporation | DOTMA, sodium deoxycholate | 85–91 | From − 1 to + 8 | [87] |
Ovalbumin | Evaluation of antigen productions via microneedles | Thin film hydration | PC, sodium cholate, steatrylamine | 122–199 | + 40 | [89] |