Fig. 7
SIRPB1 and SYK in Glioma-Macrophage Interaction. A Co-IP analysis of SIRPB1/DAP12/SYK. B CCL2, IL-8, IL1RA levels post SIRPB1 activation. C SYK inhibitor effects on FLAG antibody stimulation. D Impact of SIRPB1 deletion on SYK phosphorylation in glioma-macrophage co-culture. E Expression of CCL2, IL-8, IL1RA with NF-κB or SYK inhibitors in co-culture. F CCL2, IL-8, IL1RA levels in U87 co-culture post FLAG antibody competition. G Schematic diagram of the action mechanism of SIRPB1