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Table 1 GO terms significantly enriched in each module (adj. p < 0.05)

From: Transcriptome and open chromatin analysis reveals the process of myocardial cell development and key pathogenic target proteins in Long QT syndrome type 7

Time

Module

No. of genes

Adj. p value

GO terms (BP) ID

Description

Day0

Turquoise

3322

6.20e−08

GO:0044786

Cell cycle DNA replication

3.22e−05

GO:0000075

Cell cycle checkpoint

3.92e−08

GO:0000070

Mitotic sister chromatid segregation

7.99e−09

GO:0140014

Mitotic nuclear division

1.27e−10

GO:0071103

DNA conformation change

Day2

Green

482

0.011

GO:0048332

Mesoderm morphogenesis

0.001

GO:0007498

Mesoderm development

0.011

GO:0001707

Mesoderm formation

2.82e−05

GO:0001756

Somitogenesis

4.50e−06

GO:0009952

Anterior/posterior pattern specification

Day4

Yellow

685

0.011

GO:0048562

Embryonic organ morphogenesis

0.026

GO:0048568

Embryonic organ development

Day8

Red

568

0.035

GO:0060914

Heart formation

0.004

GO:0048562

Embryonic organ morphogenesis

0.011

GO:0072091

Regulation of stem cell proliferation

Day15

Brown

2333

1.69e−07

GO:0140053

Mitochondrial gene expression

4.64e−12

GO:0070125

Mitochondrial translational elongation

2.00e−20

GO:0006119

Oxidative phosphorylation

3.59e−17

GO:0042775

Mitochondrial ATP synthesis coupled electron transport

1.10e−13

GO:0046034

ATP metabolic process

Day30

Blue

3064

1.39e−12

GO:0060047

Heart contraction

6.11e−08

GO:0002027

Regulation of heart rate

2.14e−07

GO:0086001

Cardiac muscle cell action potential

1.41e−06

GO:0061337

Cardiac conduction

5.45e−10

GO:0060537

Muscle tissue development