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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Transcriptome and open chromatin analysis reveals the process of myocardial cell development and key pathogenic target proteins in Long QT syndrome type 7

Fig. 5

Screening target genes and transcription factors in the homogeneity module. A The fishplot shows the expression proportion (i.e., expression importance) of the six modules at different stages of differentiation and development. The abscissa represents time, and the ordinate represents the gene expression level. B–G The upper part shows a heatmap of the expression of genes in different modules at different periods, and the lower circular bar chart shows the top 100 genes with weighted importance and their rankings in each module. The mesh map shows the top 20 most important genes and their relationships in the module. The higher the weight is, the larger the icon, and the stronger the interaction, and the thicker the line. Red font indicates important TFs identified by alignment with human TF data from a public database (the JASPAR human database)

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