Fig. 1

QA improved atherosclerotic disease characterization in HFD-induced Apoe−/− mice. (A-B) Changes of body weight, liver/body weight, kidney/body weight, fat/body mass index in mice. (C-D) HE and Oil Red O staining were used to observe the pathological changes of vascular plaques. Scale bar = 250, 100, and 40 μm. (E-F) The expression of Mac-3 (positive macrophages) and SM22α (positive smooth muscle cells) was investigated by IHC. Scale bar = 250, 100, and 40 μm. *P < 0.05 vs. NC, #P < 0.05 vs. HFD, &P < 0.05 vs. HFD + QA