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Table 2 Baseline and post-45-day VLCKD dysbiosis and oxidative stress parameters of women with acne and obesity

From: Very low-calorie ketogenic diet (VLCKD): a therapeutic nutritional tool for acne?

Parameters (N = 31)

Baseline

Post 45 days of active phase of VLCKD

p-value

∆%

TMAO (µM)

5.20 ± 1.70

2.60 ± 1.39

<0.001

− 51.97 ± 15.98

dROMS (U Carr)

369.65 ± 50.78

224.64 ± 58.89

<0.001

− 38.07 ± 18.40

 Normal (250–300 U Carr) (n, %)

28 (90.3)

χ2 = 47.48, p<0.001

 

 Borderline (300–320 U Carr) (n, %)

2 (6.5)

1 (3.2)

χ2 = 0.01, p = 0.999

 

 Mild oxidative stress (321–340 U Carr) (n, %)

8 (25.8)

2 (6.5)

χ2 = 2.98, p = 0.084

 

 Moderate oxidative stress (341–400 U Carr) (n, %)

14 (45.2)

χ2 = 15.59, p<0.001

 

 High oxidative stress (401–500 U Carr) (n, %)

7 (22.6)

χ2 = 5.80, p=0.016

 
  1. VLCKD very low-calorie ketogenic diet, Δ% percentage change, dROMS reactive oxygen metabolites, TMAO trimethylamine n-oxide
  2. A p-value in bold type denotes a significant difference (p < 0.05)