Table 1 Results of the posterior probability obtained from co-localization analyses
Exposure | Outcome | nSNPs | Chr | Position | PP.H0.abf | PP.H1.abf | PP.H2.abf | PP.H3.abf | PP.H4.abf | Colocalized SNP |
|---|---|---|---|---|---|---|---|---|---|---|
AD family history (ebi-a-GCST005921) | Alzheimer's disease (ebi-a-GCST90027158) | 473 | 19 | 45411941 ± 100000 bp (around lead SNP: rs429358) | 0.00% | 0.00% | 0.00% | 0.00% | 100.00% | rs117310449 |
247 | 7 | 99716871–99919113 bp (around PVRIG gene loci) | 0.00% | 0.04% | 0.00% | 0.81% | 99.14% | rs6979218 | ||
PVRIG (eqtl-a-ENSG00000213413) | AD family history (ebi-a-GCST005921) | 301 | 7 | 99719480 ± 100000 bp (around lead SNP: rs60458236) | 0.00% | 0.00% | 0.57% | 18.97% | 80.46% | rs705867 |
Alzheimer's disease (ebi-a-GCST90027158) | 396 | 7 | 99719480 ± 100000 bp (around lead SNP: rs60458236) | 0.00% | 0.00% | 0.00% | 28.79% | 71.21% | rs55796551 |