Fig. 4
From: Characterizing and forecasting neoantigens-resulting from MUC mutations in COAD
Five MUC genes comprehensive analysis of tumor-infiltrating immune cells (B cell, CD8+ T cell, CD4+ T cell, Macrophage, Neutrophil, Dendritic cell) in COAD using the Timer database. A MUC16; B MUC4; C MUC5B; D MUC17; E MUC2. The mutation module compares the levels of immune infiltrates with or without the presence of a given mutation. Box plots are generated for each immune subset, to compare the distributions of immune infiltration levels under different gene mutation statuses, with statistical significance estimated using a two-sided Wilcoxon rank-sum test