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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: AURKB promotes bladder cancer progression by deregulating the p53 DNA damage response pathway via MAD2L2

Fig. 1

AURKB is highly expressed and is strongly associated with prognosis in BC. A Differential AURKB expression in various types of tumor tissues and adjacent normal tissues was analyzed by TIMER 2.0 database. B Differential AURKB expression in BC tissues and normal bladder tissues in unpaired and paired samples. C Representative IHC images of AURKB in BC tissues and adjacent normal tissues. H-score of AURKB expression in the clinical tumor and adjacent normal tissues of 10 BC patients. D RT-qPCR analyses of mRNA expression levels of AURKB between paired BC tissues and adjacent normal tissues. E The ROC curve analysis indicated the high-expression specificity of AURKB in tumor and normal tissues in TCGA. F Kaplan–Meier survival curves for OS and DSS comparing the high and low expression of AURKB in the GSE13507 database. (The magnification under the microscope is shown as marked in the figure. *p < 0.05, **p < 0.01, *** p < 0.001)

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