Table 1 Baseline information of DCM patients
Factor | Total no. of participants (n = 24) | Low HTRA1 expression (n = 12) | High HTRA1 expression (n = 12) | p-value |
|---|---|---|---|---|
Gender | 0.22 | |||
 Male | 21 (87.5%) | 12 (100%) | 9 (75%) |  |
 Female | 3 (12.5%) | 0 (0%) | 3 (25%) |  |
Age (year) | 44.08 ± 14.38 | 42.75 ± 14.4 | 45.42 ± 14.87 | 0.66 |
BNP | 10.01 ± 1.03 | 9.45 ± 0.81 | 10.65 ± 0.89 | 0.01 |
NT-proBNP | 12.06 ± 1.67 | 11.83 ± 1.89 | 12.28 ± 1.47 | 0.71 |
HS-TnI | 5.69 ± 3.27 | 5.65 ± 3.27 | 5.73 ± 3.44 | 0.96 |
Height (m) | 1.67 ± 0.11 | 1.67 ± 0.14 | 1.67 ± 0.06 | 0.99 |
Weight (kg) | 63 ± 19.9 | 65.75 ± 20.19 | 60 ± 20.1 | 0.5 |
BMI (kg/m2) | 22.16 ± 5.45 | 22.92 ± 4.6 | 21.32 ± 6.38 | 0.49 |
LVEF (%) | 25 ± 6.79 | 24.42 ± 6.95 | 25.58 ± 6.88 | 0.68 |
NYHA | 0.48 | |||
 III | 2 (8.3%) | 2 | 10 |  |
 IV | 22 (92.7%) | 0 | 12 |  |
EDV(ml) | 433 ± 136.7 | 420.2 ± 150 | 447.1 ± 126.4 | 0.65 |
ESV(ml) | 366.9 ± 129.5 | 350.4 ± 139.6 | 384.9 ± 121.5 | 0.54 |
SV(ml) | 66.01 ± 21.1 | 69.76 ± 26.18 | 61.93 ± 13.79 | 0.39 |
LVEDVi (ml/m2) | 245.9 ± 63.75 | 228.9 ± 63.07 | 264.5 ± 61.96 | 0.19 |
LVESVi (ml/m2) | 207.3 ± 61.1 | 189 ± 58.24 | 227.3 ± 60.36 | 0.14 |
LVEF (%) CMR | 16.1 ± 6.42 | 17.59 ± 7.86 | 14.46 ± 4.14 | 0.25 |
CI l/(min m2) | 2.96 ± 1.57 | 3.27 ± 2.09 | 2.62 ± 0.61 | 0.33 |
SV(ml/m2) | 39.69 ± 16.33 | 42.06 ± 21.35 | 37.09 ± 8.45 | 0.48 |
LV mass(g) | 176.1 ± 65.8 | 178.4 ± 59.68 | 173.7 ± 74.8 | 0.87 |
LVMi (g/m2) | 99.58 ± 31 | 97.04 ± 21.65 | 102.4 ± 39.78 | 0.69 |
HCT (%) | 40.64 ± 5.85 | 42.08 ± 6.24 | 39.2 ± 5.29 | 0.24 |
Native T1 (ms) | 1355 ± 58.26 | 1327 ± 45.92 | 1383 ± 57.2 | 0.015 |
ECV (%) | 35.69 ± 5.93 | 32.86 ± 5.21 | 38.52 ± 5.37 | 0.016 |
LGE | 0.64 | |||
 LGE(−) | 6 (25%) | 4 (33.3%) | 2 (16.7%) |  |
 LGE( +) | 18 (75%) | 8 (66.7%) | 10 (83.3%) |  |
LGE percent (%) | 11.45 ± 14.11 | 5.15 ± 7.67 | 17.74 ± 16.46 | 0.025 |