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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Exosomes from senescent epithelial cells activate pulmonary fibroblasts via the miR-217-5p/Sirt1 axis in paraquat-induced pulmonary fibrosis

Fig. 7

Suppression of miR-217-5p ameliorates PQ-induced pulmonary fibrosis. A, B qPCR analysis of the expression of miR-217-5p A and Sirt1 B in the lung tissues from PQ-poisoned mice with or without the treatment of miR-217-5p antagomir. n = 5 per group. C Western blot analysis of the acetylation levels of β-catenin in in the lung tissues from mice treated as in (A). D The representative H&E staining (up panel) and Masson’s trichrome staining (down panel) images of the lung tissues from mice treated as in (A). E The analysis of hydroxyproline in the lung tissues from mice treated as in (A). F qPCR analysis of the expression of Acta2 and Col1a1 in the lung tissues from mice treated as in (A). All data were presented as the means ± SEM. **P < 0.01

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