Skip to main content
Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Exosomes from senescent epithelial cells activate pulmonary fibroblasts via the miR-217-5p/Sirt1 axis in paraquat-induced pulmonary fibrosis

Fig. 6

miR-217-5p activates fibroblasts via SIRT1/β-catenin axis. A Representative images and quantification of immunofluorescent detection for β-catenin (Red) in pulmonary fibroblasts transfected with or without miR-217-5p mimic. B Western blot analysis of the expression of β-catenin in pulmonary fibroblasts transfected with or without miR-217-5p mimic and co-transfected with or without LV-SIRT1. C Western blot analysis of the acetylation levels of β-catenin in pulmonary fibroblasts transfected with or without SIRT1 siRNA (si-SIRT1). D Western blot analysis of the acetylation levels of β-catenin in pulmonary fibroblasts transfected with or without miR-217-5p mimic and co-transfected with or without LV-SIRT1. All data were presented as the means ± SEM. *P < 0.05

Back to article page