Fig. 2

Screening lncRNAs associated with tumor metastasis in relatively high metastatic cell lines. A GSEA analysis was used to identify differential genes profiles between lim2-NOZ and NOZ cells. B Up-regulated genes in EMT pathway were found in lim2-NOZ compared to NOZ cells. C Protein levels of N-cadherin, E-cadherin, and Vimentin in lim2 and parent cells. D Co-upregulated lncRNAs in two high-throughput data were showed by Venn diagram. E Candidate lncRNAs were verified in lim2-NOZ and lim2-GBC-SD cells. F Three candidate lncRNAs were detected in 6 paired GBC tissues, including normal tissues, tumor tissues and liver metastases (Paired t test)