Fig. 1

Mutation patterns in patients with myelodysplastic syndrome between the MF-0/1 and MF-2/3 cohorts, who were treated with allogeneic hematopoietic stem cell transplantation (N = 137). A Overview of gene mutation spectrum. The plot represents a graphical summary of the distribution of somatic lesions in sequenced genes across the set of patients. Columns represent samples and rows represent genes. Their number per sample and per gene is summarized on the top and on the left side of the plot, respectively. B Circos diagram depicts the relative frequency and pairwise co-occurrence of mutations. C Frequency of gene mutations according to the MF grade