Fig. 7

Analysis of intercellular communication among various cell types in the HLA-B27-negative and -positive groups. A Bar graph illustrating the quantity and strength of cell communication between the HLA-B27-negative and HLA-B27-positive groups. B Chord plot of the quantity and strength of cell communication among different cell types in the HLA-B27-negative and HLA-B27-positive groups. C Scatter plot representing the relative strength of cell communication for each cell type within the respective groups. D Specific cell communication pathways unique to the HLA-B27-negative and -positive groups. E The incoming strength of intergroup-specific pathways within various cell types. F The outcoming strength of intergroup-specific pathways within various cell types. G–I Presentation of specific pathways (the APP pathway, the SELPLG pathway and the CADM pathway) exclusive to the HLA-B27-positive group, depicting the direction of cell communication indicated by arrows. J The correlation between expression of AIF1 and that of the receptor for the APP pathway (CD74)