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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches

Fig. 2

Analysis of specific gene-signatures in GBM, MM-BM and MM cell lines. Starting from whole genome profiling data of GBM (#14), MM-BM (#12) and MM (#11) cell lines, violin plots report the median value of genes expression related to EMT process (#62 genes) modified from MSigDB-GSEA [30] A, multi-stage differentiation profile (#517 genes; GBM:grey; MM-BM:blue; MM:light blue) B, or to inhibition (#14 genes) or activation (#45 genes) of MHC class II antigen processing/presentation C for each tumor cell type. Red line: median value as center; lower and upper dotted lines: 25th and the 75th percentiles, respectively. Statistical significance (p-value < 0.05) assessed by ordinary one-way ANOVA

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Journal of Translational Medicine

ISSN: 1479-5876

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