Fig. 1

Hierarchical clustering and enrichment analyses of the most variable probes among GBM, MM-BM, and MM cells. A Heatmap of Log2 constitutive values of 11,112 DEG (p-value < 0.05) clustered according to Euclidean distance between data from whole genome profiling of GBM (#14), MM-BM (#12) and MM (#11) cell lines. B Gene Set Enrichment Analysis of genes belonging to each cluster performed by EnrichR tool. X axis reports the Combined Score of significant enriched GO terms. Size of the dot represents the significance of GO terms; colour of the dot represents the different cluster identified by the clustering technique