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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Identification of therapeutic targets in osteoarthritis by combining heterogeneous transcriptional datasets, drug-induced expression profiles, and known drug-target interactions

Fig. 6

Network construction. The figure shows a sub-graph extracted from the PPI graph filtered by considering only DE up consensus genes (blue) and the targeted genes (green) of the top 50 drugs (red, rank value reported). Those links represent the STRING combined score greater than 500. Single genes that had only low-scoring connections or none of them, and our Genes that did not match those of STRING, were not shown

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