Fig. 5

The potential pathway of TIM3-mediated CD8⁺TILs exhaustion in DLBCL. (a–c Single cell level). The expression of LGALS9 (a) and the characteristic genes of M2 macrophage (CD163 and MRC1/CD206) (b) for 24 cell clusters in DLBCL; c interaction network of TIM3/Galectin-9 pathway in DLBCL; d (histology level) the correlation between LGALS9 and CD163, and MRC1/CD206 detected by RNA sequencing