Table 1 Assessing the causal effects of LDL cholesterol on the risk of Nonalcoholic fatty liver disease and acute pancreatitis
Exposure | Outcome | Method | nSNP | Pval | OR | MRPresso-Pval |
|---|---|---|---|---|---|---|
LDL cholesterol | Non-alcoholic fatty liver disease | Inverse variance weighted (fixed effects) | 73 | 0.01 | 0.71 (0.54–0.94) | 0.054 |
MR Egger | 73 | 0.07 | 0.66 (0.42–1.03) |  | ||
Weighted median | 73 | 0.04 | 0.66 (0.44–0.98) |  | ||
Weighted mode | 73 | 0.03 | 0.69 (0.49–0.97) |  | ||
LDL cholesterol | Acute pancreatitis | Inverse variance weighted (fixed effects) | 74 | 0.04 | 0.85 (0.73–0.99) | 0.11 |
MR Egger | 74 | 0.06 | 0.80 (0.63–1.01) |  | ||
Weighted median | 74 | 0.20 | 0.86 (0.68–1.08) |  | ||
Weighted mode | 74 | 0.10 | 0.84 (0.68–1.03) |  |