Table 1 Details of GWAS summary data and LDSC of single-trait heritability
Traits | Original study (year) | ID | Sample size | Number of cases | Number of controls | Ethnicity | Global h2 (SE) | λGC |
|---|---|---|---|---|---|---|---|---|
MG | Ruth Chia et al. (2022) | GCST90093061 | 38,243 | 1,873 | 36,370 | European (U.S., Italy) | 0.076 (0.015) | 1.059 |
Early-onset MG | GCST90093465 | 3,313 | 595 | 2,718 | European (U.S., Italy) | 0.365 (0.135) | 1.002 | |
Late-onset LOMG | GCST90093466 | 34,930 | 1,278 | 33,652 | European (U.S., Italy) | 0.078 (0.015) | 1.044 | |
MG | – | phecode-358.1 | 324,308 | 224 | 324,074 | European (U.K.) | 0.002 (0.001) | 1.011 |
MG | – | finngen_R10_G6 | 408,891 | 461 | 408,430 | European (Finnish) | 0.001 (0.001) | 1.013 |