Fig. 2
From: A proteomic classifier panel for early screening of colorectal cancer: a case control study
Quantitative proteomic analysis of plasma samples from CRC patients and healthy controls. A Volcano plot of DDA data obtained from discovery cohort 1. Differentially expressed proteins are shown in blue (down) or red (up) circles. X-axis shows log2-fold change of plasma proteins between CRC patients and healthy subjects, and y-axis shows log10 of statistical significance values. B Volcano plot of DIA data obtained from discovery cohort 2. The label for the differentially expressed proteins and the two axes are the same as in A. C Principal component analysis of the protein expression data in cohort 1. D Principal component analysis of the protein expression data from cohort 2. E Gene ontology analysis of up-regulated proteins in the DIA data. F Gene ontology analysis of down-regulated proteins in the DIA data