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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Engineered bone marrow mesenchymal stem cell-derived exosomes loaded with miR302 through the cardiomyocyte specific peptide can reduce myocardial ischemia and reperfusion (I/R) injury

Fig. 2

Isolation and identification of exosomes derived from bone marrow mesenchymal stromal cells (BMSCs, BMSCs-EXO), as well as synthesis and characterization of DSPE-PEG-CMP-EXO and DSPE-PEG-CMP-miR302-EXO. A Morphological characteristics of BMSCs-derived exosomes (BMSCs-EXO) was observed under transmission electron microscope (TEM). Scale bar = 100 nm. B The size distribution of BMSCs-EXO was measured via the Nanoparticle tracking analysis (NTA). C Flow cytometric technique was used to analyze the specific surface markers (CD44, CD45, CD29 and CD73) of BMSCs of BMSCs-EXO. Scale bar = 100 nm. D TEM morphology of DSPE-PEG-CMP-EXO. E NTA measured size distribution of DSPE-PEG-CMP-EXO. F TEM morphology of DSPE-PEG-CMP-miR302-EXO. Scale bar = 200 nm. G The size distribution of DSPE-PEG-CMP-miR302-EXO was measured with the NTA

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