Fig. 4

Phylogenetic Tree in cSCLC. A Density plot of mutations, CCF, and phylogenetic tree in L-SCLC; B Density plot of mutations, CCF, and phylogenetic tree in A/S-SCLC. Each point in the density plot on the left panel represents a mutation, with different colors indicating different positions from the phylogenetic tree in the right panel. The right panel displays the evolutionary tree of one patient, with the trunk clone, the trunk subclone, and the two branches indicated by different colors, respectively