Skip to main content
Fig. 4 | Journal of Translational Medicine

Fig. 4

From: RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling

Fig. 4

Treatment with 2‐DG could suppressive the effect of RBBP7 facilitate HCC cell proliferation and glycolysis in vitro. Compared with shNC group *, P < 0.05, **, P < 0.01, ***, P < 0.001. ****, P < 0.0001. Compared with oeRBBP7 + Vehicle group #, P < 0.05, ##, P < 0.01, ###, P < 0.001. ####, P < 0.0001. A. CCK-8 assay was performed to examine cell growth after RBBP7 overexpression with 2-DG. B, C. A colony formation assay was conducted using RBBP7 overexpression with 2-DG. D. ATP concentration in RBBP7 overexpression with 2-DG. E. Lactic acid concentration in RBBP7 overexpression with 2-DG. F. Glucose uptake capacity of RBBP7 overexpression with 2-DG. G. NAD+/NADH colorimetric assay of RBBP7 overexpression with 2-DG. H, I. Expression of glycolysis-associated proteins (PFKM, PKM2, and LDHA) in RBBP7 overexpression with 2-DG

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us