Fig. 6
From: Hypoxia promotes metastasis by relieving miR-598-3p-restricted glycolysis in gastric cancer
miR-598-3p suppressed the metastasis of GC cells by inhibiting glycolysis. A Transwell assay of hypoxic MKN45 cells cultured in low glucose medium (L.G.M.) 1.5 mg/L or L.G.M. supplemented with glucose to 4.5 mg/L. B ATP production of hypoxic MKN45 cells in A. C ATP source of hypoxic MKN45 cells in A. D Western blot analysis of MKN45 cells in A. E Transwell assay of MKN45 cells treated with hypoxia or 1 μM R406. F ATP production of hypoxic MKN45 cells in F. G ATP source of hypoxic MKN45 cells in F. H Transwell assay of MKN45 cells transfected with Sponge or treated with 1 μM R406. I ATP production of hypoxic MKN45 cells in H. J ATP source of hypoxic MKN45 cells in H. K Western blot analysis of cells in E. L Western blot analysis of cells in H. M Transwell assay of MKN45 cells transfected with miR-598-3p and then treated with hypoxia or 1 μM UK5099. N Western blot analysis of MKN45 cells in M