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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: From the identification of actionable molecular targets to the generation of faithful neuroblastoma patient-derived preclinical models

Fig. 2

Development, characterization, and therapeutic use of PDX/CPDX and 3D models. IHC immunohistochemistry, FCM flow cytometry, PDX Patient-Derived Xenograft, CDPX Cell Patient-Derived Xenograft, 3D patient-derived tumor-spheres, NB neuroblastoma, BM Bone Marrow derived from either iliac crests or tumor bone lesions, NSG NOD/SCID/IL2Rgammanull mice, nude athymic nude/nude mice, s.c. subcutaneous implant/injection of NB tumor fragments or NB cell suspension derived from tumor-infiltrated BM, orthotopic implantation/injection of NB tumor fragments or NB cell suspension derived from P2 generation mice, in the adrenal gland, WES whole exome sequencing

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Journal of Translational Medicine

ISSN: 1479-5876

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