Association of dietary flavonoid intakes with prevalence of chronic respiratory diseases in adults

Table 4 Multiple linear regression associations of dietary total flavonoid intake levels with inflammatory markers among adults in NHANES 2007–2010 and 2017–2018

	Continous flavonoid intakes		Category of flavonoid intakes
	β (95% CI)	P value	β	β (95% CI)	β (95% CI)	P_trend
CRP	− 0.04 (− 0.05, − 0.02)	< 0.01	Ref (0.00)	− 0.16 (− 0.23, − 0.09)	− 0.17 (− 0.23, − 0.11)	< 0.01
WBC	− 0.01 (− 0.01, − 0.00)	< 0.01	Ref (0.00)	− 0.03 (− 0.04, − 0.01)	− 0.04 (− 0.05, − 0.02)	< 0.01
NEU	− 0.01 (− 0.01, − 0.00)	< 0.01	Ref (0.00)	− 0.04 (− 0.06, − 0.02)	− 0.05 (− 0.07, − 0.03)	< 0.01
LYM	0.00 (− 0.01, 0.00)	0.29	Ref (0.00)	− 0.02 (− 0.04, 0.00)	− 0.02 (− 0.04, 0.00)	0.05
MON	− 0.01 (− 0.01, − 0.00)	0.01	Ref (0.00)	− 0.02 (− 0.04, − 0.01)	− 0.02 (− 0.04, − 0.01)	0.01
RDW	− 0.03 (− 0.04, − 0.02)	< 0.01	Ref (0.00)	− 0.16 (− 0.23, − 0.10)	− 0.14 (− 0.19, − 0.09)	< 0.01

CI, confidence interval; CRP, C-reactive protein; WBC, white blood cell count; NEU, neutrophil count; LYM, lymphocyte count; MON, monocyte count; RDW, red blood Cell distribution width. Model was adjusted as age (< 40, 40–59, or > 59), sex (male or female), race/ethnicity (Mexican American, Other Hispanic, Non-Hispanic White, Non-Hispanic Black or Other), education level (below high school, high school, or above high school), family poverty income ratio (≤ 1.0, 1.1–3.0, or > 3.0), smoking status (never smoker, former smoker, or current smoker), energy intake levels (in tertiles), metabolic syndrome (yes or no), and supplement use (yes or no)

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