Fig. 6

Inhibition of ACACA ameliorates PAOA-induced intracellular mitochondrial dysfunction. A Representative image of MMP with high connotation live cell imaging. Blue recaptures the nucleus, Red presents JC-10 polymer and green presents JC-10 monomer. Scale bars, 50 μm. B The quantitative fluorescence intensity of JC-10. C The content of ATP in cells. Data are the mean ± SEM from 3 independent experiments. Values with different letters are significantly different in the groups (^*P < 0.05 and ^**P < 0.01 compared with the Control group, ^#P < 0.05 and ^##P < 0.01 compared with the PAOA group)