Fig. 3
From: Systematic integration of molecular and clinical approaches in HCV-induced hepatocellular carcinoma
MiRNAs target interactive networks in regulating HCV-HCC. A Heatmap of disease-specific survival-associated miRNA target expression between tumor (T) and adjacent non-tumor (ANT) samples in the HCV-HCC cohort B Relative expression of L-HCV miRNAs (hsa-miR-215-5p, hsa-miR-10b-5p, hsa-let-7a-5p) compared to S-HCV. C An interactive network of miRNAs, miRNA-target RCN1, oncogene MYC and EMT marker Vimentin (VIM). D ICC staining imaging at 40X magnification of EMT marker Vimentin (VIM) expression in Huh-7.5.1 and L-HCV cells. DAPI (4’,6-diamidino-2-phenylindole): Cell Nuclear Staining. Merged images of VIM expression and cells. Experiments were conducted in triplicates. E Expression of VIM between Huh-7.5.1 and L-HCV. Statistical significance p < 0.05*, p < 0.01**. paired t test