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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target

Fig. 1

Differential expression level of DLGAP5 mRNA and protein in LUAD. A The comparative expression of DLGAP5 mRNA between pan-cancers including LUAD and normal tissues in TCGA & GTEx databases (*P < 0.05; ***P < 0.001). B Comparison of DLGAP5 mRNA expression between LUAD and normal tissues in TCGA & GTEx databases (***P < 0.001). C Comparison of DLGAP5 mRNA expression between LUAD and corresponding matched-normal tissues in TCGA database (***P < 0.001). D–F Comparison of DLGAP5 mRNA expression between LUAD and normal tissues in independent GEO datasets: GSE31210, GSE43458 and GSE30219 (***P < 0.001). G–H Comparison of DLGAP5 mRNA expression between LUAD and corresponding matched-normal tissues in independent GEO datasets: GSE32863 and GSE75037 (***P < 0.001). I Representative images of DLGAP5 protein level in LUAD detected by IHC staining in HPA database. J Comparison of DLGAP5 protein expression between LUAD and normal tissues in CPTAC database (***P < 0.001). (K) Western blot analysis of DLGAP5 protein expression level in LUAD cell lines (A549, H1299, H1993, PC9, H3255, H1975) and the normal lung epithelial cell line (BEAS-2B)

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