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Table 1 Comparison of clinical characteristics between IPN group and Non-IPN group in the training cohort

From: Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis

Index

Non-IPN group

(n = 176)

IPN group

(n = 26)

Z/χ2

value

P value

Age [M (QL, QU)]

47.00 (36.00, 55.00)

40.50 (35.75, 51.25)

− 1.142

0.254

ARDS [n (%)]

23.00 (13.10)

7.00 (26.90)

3.439*

0.064

SIRS [n (%)]

63.00 (35.80)

20.00 (76.90)

15.830*

< 0.001

ICU [n (%)]

65.00 (36.90)

23.00 (88.00)

24.466*

< 0.001

Number of days in ICU [M (QL, QU)]

0.00 (0.00,7.00)

12.00 (5.25, 26.75)

− 5.490

< 0.001

MOF [n (%)]

24.00 (13.60)

10.00 (38.40)

9.973*

0.002

Male [n (%)]

133.00 (75.60)

18.00 (69.20)

0.482*

0.487

Local complications [n (%)]

80.00 (45.50)

21.00 (80.70)

11.301*

0.001

Systemic complications [n (%)]

34.00 (19.30)

15.00 (57.70)

4.873*

0.027

Death [n (%)]

4.00 (2.30)

4.00 (15.40)

10.239*

0.001

CRP [mg/L, M (QL, QU)]

51.10 (0.16, 151.51)

80.56 (27.55, 172.38)

− 1.367

0.172

WBC [ × 109/L, M (QL, QU)]

10.43 (7.55, 13.82)

11.04 (8.33, 14.98)

− 0.798

0.425

N [ × 109/L, M (QL, QU)]

8.24 (5.75, 11.69)

9.51 (7.18, 12.75)

− 1.333

0.182

PCT [μg/L, M (QL, QU)]

0.06 (0.05, 0.29)

0.83 (0.18, 4.01)

− 4.372

< 0.001

SOFA [M (QL, QU)]

1.00 (0.00, 3.00)

3.00 (2.00, 5.25)

− 4.529

< 0.001

APACHE II [M (QL, QU)]

4.00 (2.00,8.00)

18.50 (13.00, 24.25)

− 7.058

< 0.001

IG [%, M (QL, QU)]

0.50 (0.30, 0.70)

0.85 (0.40, 1.20)

− 2.983

0.003

nCD64 index [M (QL, QU)]

1.25 (1.01, 1.54)

2.42 (1.91, 2.86)

− 5.899

< 0.001

Etiology [n (%)]

3.381*

0.337

 Biliogenic [n (%)]

67.00 (38.10)

8 (30.70)

  

 Lipogenic [n (%)]

63.00 (35.80)

9.00 (34.60)

  

 Alcohol [n (%)]

24.00 (13.60)

7.00 (26.90)

  

 Other [n (%)]

22.00 (12.50)

2.00 (7.80)

  
  1. nCD64 index neutrophil CD64 index, WBC white blood cells, N neutrophils, APACHE II acute physiological and chronic health score, ARDS acute respiratory distress syndrome, SIRS systemic inflammatory response syndrome, MOF multiple organ failure, CRP C reactive protein, PCT procalcitonin, IG immature granulocyte, SOFA sequential organ failure assessment, IPN infected pancreatic necrosis. M (QL, QU) median (lower quartile, upper quartile)
  2. The “*” symbol represents results obtained through chi-square test