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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Prevention of neointimal hyperplasia after coronary artery bypass graft via local delivery of sirolimus and rosuvastatin: network pharmacology and in vivo validation

Fig. 6

Prediction of the drug combination of sirolimus and rosuvastatin for CABG via PPI network analysis. A–C The interactive PPI network of A CABG and sirolimus, B CABG and rosuvastatin, and C CABG and both drugs. The top 10 hub and bottleneck genes identified using CytoHubba are shown. Dark red color indicates a relatively higher maximal clique centrality or bottleneck score. The figures were created using BioRender. CABG coronary artery bypass graft, PPI protein–protein interaction

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