Skip to main content
Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Hypoxia-induced P4HA1 overexpression promotes post-ischemic angiogenesis by enhancing endothelial glycolysis through downregulating FBP1

Fig. 5

Inhibition of endothelial glycolysis counteracts P4HA1-mediated angiogenesis. HUVECs were treated with Ad-NC, Ad-P4HA1 alone, or Ad-P4HA1 and 2-DG (5 mM) for 24 h. A EdU incorporation assay, B transwell migration assay, and C tube formation assay were performed. Data were analyzed by one-way ANOVA followed by Bonferroni post hoc test (n = 3). *p < 0.05. NC negative control, 2-DG 2-deoxyglucose

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us