Skip to main content
Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms

Fig. 3

Knockdown of ACSS2 suppressed pNENs cells viability. A–C pNENs cell lines stably knockdown of ACSS2 was constructed and assayed by qRT-PCR and WB. D, E CCK-8 assay indicated that knockdown of ACSS2 inhibited pNENs cells proliferation. F, G The colony formation indicated that knockdown of ACSS2 suppressed pNENs cells proliferation. H, I Knockdown of ACSS2 significantly inhibited DNA synthesis. J, K Knockdown of ACSS2 successfully inhibited the migration and invasion of pNENs cells. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us