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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms

Fig. 2

Overexpression of ACSS2 promoted pNENs cells viability. A–C pNENs cell lines stably overexpression of ACSS2 was constructed and assayed by qRT-PCR and WB. D, E CCK-8 assay showed that overexpression of ACSS2 promoted pNENs cell proliferation rate. F, G The colony formation indicated that overexpression of ACSS2 promoted pNENs cells proliferation. H, I Overexpression of ACSS2 significantly stimulated DNA synthesis. J, K Overexpression of ACSS2 successfully promoted the migration and invasion of pNENs cells. **p < 0.01, ***p < 0.001, ****p < 0.0001

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Journal of Translational Medicine

ISSN: 1479-5876

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