Fig. 6

Transcriptomic analysis of tumor suppressive immune microenvironment associated with high-DPS. A Heatmap shows the expression levels of differentially expressed genes between high- and low-DPS groups with TCGA-STAD profile. B Volcano plot shows the differentially expressed genes in the high-DPS group compared with the low-DPS group. C Comparison of the abundance of MDSCs between high- and low-DPS groups; D Normalized mRNA expression levels of immune co-inhibitor between low- and high-DPS groups. E GSEA results showing the enrichment of six representative pathways in the high-DPS group. MDSCs, myeloid-derived suppressor cells; GSEA, gene set enrichment analysis