Journal of Translational Medicine

Table 1 Univariate and multivariate analyses of CENPA mRNA level and patient disease-free survival (DFS)

From: EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression

Variable	Univariate analysis			Multivariate analysis ^c
Variable	HR ^a	90%CI ^b	P	HR ^a	90%CI ^b	P
Disease-free survival (n = 486)
EXO1
Low (n = 242)	0.297	0.173–0.510	0.0002	0.506	0.285–0.899	0.05
High (n = 244)	0.297	0.173–0.510	0.0002	0.506	0.285–0.899	0.05
Age
< 60 (n = 197)	0.642	0.395–1.043	0.133	0.875	0.537–1.426	0.654
> 60 (n = 289)	0.642	0.395–1.043	0.133	0.875	0.537–1.426	0.654
T stage
T2 (n = 190)	0.244	0.144–0.412	0.0001	0.473	0.266–0.840	0.032
T3 or T4 (n = 296)	0.244	0.144–0.412	0.0001	0.473	0.266–0.840	0.032
Gleason score
Gleason 6/7 (n = 288)	0.244	0.144–0.412	0.00001	0.473	0.266–0.840	0.032
Gleason 8/9/10 (n = 198)	0.244	0.144–0.412	0.00001	0.473	0.266–0.840	0.032

^a Hazard ratio, estimated from the Cox proportional hazard regression model
^b Confidence interval of the estimated HR
^c Multivariate models were adjusted for age, T stage, and Gleason score

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ISSN: 1479-5876

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