Fig. 2

EXO1 was a good biomarker and highly expressed in PCa. A The top 30 genes most relevant to Gleason and T staging in each pink module were selected as gene sets. The genes associated with proliferation and P53 were also selected as the other two gene sets. These four gene sets were utilized to make a Wayne diagram. B–E Using the TCGA-PRAD project and the GSE6919 project, unpaired versus paired EXO1 expression was demonstrated. F Using the TCGA-PRAD project, EXO1 expression levels were demonstrated with different T stage. G–H Using the TCGA-PRAD project and the GSE6919 project, the ROC curves of EXO1 were displayed. I The DFS curve of EXO1 using TCGA-PRAD project. J–L A chi-square analysis was utilized to demonstrate the relationship between EXO1 expression levels and T stage, Gleason score, and recurrence. M The EXO1 relative RNA expression in PCa tissues. N The EXO1 protein expression of PCa tissues. O IHC results of EXO1 in PCa tissues