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Table 3 The expression of ANGPTL4 in ovarian cancer based on TCGA database

From: ANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway and interacting with ESM1

characteristics

Low expression of ANGPTL4

High expression of ANGPTL4

p value

n

190

191

 

Clinical stage, n (%)

  

0.4442

 Stage I and Stage II

9 (2.4%)

15 (4%)

 

 Stage III

150 (39.7%)

146 (38.6%)

 

 Stage IV

30 (7.9%)

28 (7.4%)

 

Tumor status, n (%)

  

0.2177

 Tumor free

40 (11.8%)

32 (9.5%)

 

 With tumor

126 (37.3%)

140 (41.4%)

 

Histologic grade, n (%)

  

0.5159

 G1&G2

25 (6.7%)

21 (5.7%)

 

 G4&G3

160 (43.1%)

165 (44.5%)

 

Venous invasion, n (%)

  

0.5253

 No

25 (23.8%)

16 (15.2%)

 

 Yes

35 (33.3%)

29 (27.6%)

 

Lymphatic invasion, n (%)

  

0.9361

 No

26 (17.4%)

22 (14.8%)

 

 Yes

54 (36.2%)

47 (31.5%)

 

ESM1, n (%)

  

0.0018

 Low

110 (28.9%)

80 (21%)

 

 High

80 (21%)

111 (29.1%)

 

VEGFA, n (%)

  

2.29E-07

 Low

120 (31.5%)

70 (18.4%)

 

 High

70 (18.4%)

121 (31.8%)

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