Fig. 5

ACACA and its inhibitor ND630 regulate PCa cell activity in vitro. A–D CCK8, Colony formation, wound healing, and Transwell invasion assays were performed in DU145 cells treated with control, siACACA, ND630, and siACACA + ND630. E Western blot assay was used to determine the ACACA and p-AMPK levels in DU145 PCa cells with different treatments. β-actin was used as a loading control. One-way ANOVA test and Kruskal–Wallis test were used for the statistical analyses. ^**P < 0.01, ^***P < 0.001