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Table 1 Clinical Information of the validation cohort

From: Multiplex immunohistochemistry defines two cholesterol metabolism patterns predicting immunotherapeutic outcomes in gastric cancer

Characteristic

N = 35

Age [M (range), year]

58 (24–78)

Gender [n (%)]

 

 Male

26 (74.29)

 Female

9 (25.71)

Location [n (%)]

 

 Upper 1/3

12 (34.29)

 Middle 1/3

10 (28.57)

 Lower 1/3

10 (28.57)

 Whole

1 (2.86)

 Remnant

2 (5.71)

Tumor invasion [n (%)]

 

 T2

4 (11.43)

 T3

4 (11.43)

 T4a

19 (54.28)

 T4b

8 (22.86)

Lymph node [n (%)]

 

 N0

1 (2.86)

 N1–3

34 (97.14)

Distant metastasis [n (%)]

 

 M0

17 (48.57)

 M1

18 (51.43)

cTNM stage [n (%)]

 

 2A

3 (8.57)

 2B

1 (2.86)

 3

9 (25.71)

 4A

4 (11.43)

 4B

18 (51.43)

Differentiation [n (%)]

 

 Moderate

5 (14.29)

 Poor

30 (85.71)

Anti-PD-1 agent [n (%)]

 

 Camrelizumab

11 (31.43)

 Tislelizumab

1 (2.86)

 Pembrolizumab

3 (8.57)

 Nivolumab

8 (22.85)

 Sintilimab

12 (34.29)

 Received cycles of anti-PD-1 therapy [M (range)]

3 (2–11)

Chemotherapy [n (%)]

 

 SOX

33 (94.28)

 CapeOx

1 (2.86)

 Paclitaxel plus carboplatin

1 (2.86)

 Follow-up time [M (range), months]

6.9 (1.7–18.2)

 PFS [M (range), months]

6.3 (1.7–17.0)

 OS [M (range), months]

13.7 (1.7–18.2)

  1. M median, SOX S-1 plus Oxaliplatin, CapeOx capecitabine plus Oxaliplatin, PFS progression free survival, OS overall survival