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Table 2 Characteristics of patients who underwent chemotherapy

From: Hypoxia-inducible factor 1α modulates interstitial pneumonia-mediated lung cancer progression

Patient characteristic

IP ( +)

IP (−)

P

Participants, n

n = 13

n = 13

 

Age (years)

69.0 (68.0–74.0)

68.0 (65.5–72.5)

0.254

Sex, male/female

12/1

11/2

0.535

ECOG PS

 0/1/2

7/4/2

7/5/1

0.798

Smoking history

 Pack-years

50.0 (45.0–63.0)

47.0 (42.5–73.5)

0.938

COPD

  +/−

12/1

11/2

0.535

Clinical stage

 IIIA/IIIB/IVA/IVB

1/0/7/5

1/0/10/2

0.394

Histology

0.489

 Adenocarcinoma

11

12

 

 Squamous cell carcinoma

1

1

 

 Others

1

0

 

 KL-6, U/mL

949.0 (446.0–1683.0)

461.0 (214.0–771.0)

0.039

 CEA

10.5 (5.5–21.6)

42.7 (6.1–307.4)

0.127

 CYFRA

9.7 (3.5–14.3)

5.2 (1.7–5.8)

0.036

  1. Data are expressed as frequency or median (interquartile range). IP interstitial pneumonia, ECOG PS eastern cooperative oncology group performance status, COPD chronic obstructive pulmonary disease, KL-6 Krebs von den Lungen-6, CEA carcinoembryonic antigen, CYFRA cytokeratin 19 fragment