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Table 1 Characteristics of patients who underwent surgery

From: Hypoxia-inducible factor 1α modulates interstitial pneumonia-mediated lung cancer progression

Patient characteristic

IP ( +)

IP (−)

P

Participants, n

n = 24

n = 24

 

Age (years)

74.0 (69.5–77.0)

72.5 (67.2–78.0)

0.901

Sex, male/female

20/4

23/1

0.143

ECOG PS, 0/1

18/6

18/6

1.000

Smoking history, pack-years

48.0 (26.2–75.0)

60.0 (42.5–87.5)

0.301

COPD, ± 

7/17

9/15

0.539

Pathological stage, I/II/IIIA/IIIB

16/3/4/1

18/4/2/0

0.507

Histology

0.933

 Adenocarcinoma

8

8

 

 Squamous cell carcinoma

11

10

 

 Others

5

6

 

Surgical procedure

0.944

 Lobectomy

10

11

 

 Segmentectomy

6

6

 

 Partial resection

8

7

 

KL-6, U/mL

482.0 (306.7–771.5)

262.5 (204.7–341.0)

 < 0.001

CEA

4.9 (2.8–9.8)

3.2 (2.4–3.9)

0.012

CYFRA

4.0 (2.3–4.6)

2.5 (1.8–4.9)

0.132

  1. Data are expressed as frequency or median (interquartile range). IP interstitial pneumonia, ECOG PS eastern cooperative oncology group performance status, COPD chronic obstructive pulmonary disease, KL-6 Krebs von den Lungen-6, CEA carcinoembryonic antigen, CYFRA cytokeratin 19 fragment