From: Hypoxia-inducible factor 1α modulates interstitial pneumonia-mediated lung cancer progression
Patient characteristic | IP ( +) | IP (−) | P |
---|---|---|---|
Participants, n | n = 24 | n = 24 | |
Age (years) | 74.0 (69.5–77.0) | 72.5 (67.2–78.0) | 0.901 |
Sex, male/female | 20/4 | 23/1 | 0.143 |
ECOG PS, 0/1 | 18/6 | 18/6 | 1.000 |
Smoking history, pack-years | 48.0 (26.2–75.0) | 60.0 (42.5–87.5) | 0.301 |
COPD, ± | 7/17 | 9/15 | 0.539 |
Pathological stage, I/II/IIIA/IIIB | 16/3/4/1 | 18/4/2/0 | 0.507 |
Histology | 0.933 | ||
Adenocarcinoma | 8 | 8 | |
Squamous cell carcinoma | 11 | 10 | |
Others | 5 | 6 | |
Surgical procedure | 0.944 | ||
Lobectomy | 10 | 11 | |
Segmentectomy | 6 | 6 | |
Partial resection | 8 | 7 | |
KL-6, U/mL | 482.0 (306.7–771.5) | 262.5 (204.7–341.0) | < 0.001 |
CEA | 4.9 (2.8–9.8) | 3.2 (2.4–3.9) | 0.012 |
CYFRA | 4.0 (2.3–4.6) | 2.5 (1.8–4.9) | 0.132 |