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Table 2 Summary of all 74 unique ARID1A-interacting proteins identified by IP-MS/MS

From: Identification and characterization of ARID1A-interacting proteins in renal tubular cells and their molecular regulation of angiogenesis

Protein name

Swissprot ID

Gene symbol

MS/MS identification score

%Cov

No. of unique/total matched peptides

MW (kDa)

14–3-3 protein zeta/delta

P63101

YWHAZ

20.18

9.0

2/2

27.77

40S ribosomal protein S12

Q76I81

RPS12

33.54

16.7

1/1

14.52

40S ribosomal protein S18

Q5TJE9

RPS18

6.18

5.3

1/1

17.72

40Sribosomal protein SA

Q4GWZ2

RPSA

34.73

9.8

2/2

32.93

60S ribosomal protein L3

Q4R5Q0

RPL3

8.75

2.2

1/1

46.05

60S ribosomal protein L31

Q5RBR9

RPL31

6.35

11.2

1/1

14.39

60Sacidic ribosomal protein P0

P19945

RPLP0

14.92

6.3

2/2

34.22

Actin, alpha cardiac muscle 1

P68032

ACTC1

6.24

22.5

1/9

42.02

Actin, cytoplasmic 1

P84336

ACTB

323.31

53.9

1/16

41.80

Actin, cytoplasmic 2

P63261

ACTG1

39.50

53.9

1/16

41.79

Alpha-enolase (Fragment)

P86210

ENO1

8.29

9.9

1/1

23.84

Caspase-14

P31944

CASP14

14.07

10.7

2/2

27.68

Cathepsin D

P07339

CTSD

13.92

6.1

2/2

44.55

Cleavage and polyadenylation specificity factor subunit 5

Q9CQF3

NUDT21

82.14

20.7

3/3

26.24

Cleavage and polyadenylation specificity factor subunit 7

Q5XI29

CPSF7

83.31

10.4

4/4

51.07

Coiled-coil domain-containing protein 39

E2R1I5

CCDC39

6.20

0.9

1/1

110.37

Cornifin-B

P22528

SPRR1B

34.12

55.1

4/4

9.89

D-3-phosphoglycerate dehydrogenase

Q61753

PHGDH

7.86

2.1

1/1

56.59

DCC-interacting protein 13-alpha

Q8K3H0

APPL1

33.13

5.0

3/3

79.33

Desmoplakin

P15924

DSP

21.59

1.0

2/2

331.77

Dolichyl-diphosphooligosaccharide protein glycosyltransferase 48 kDa subunit

Q29381

DDOST

28.26

2.5

1/1

48.86

Dolichyl-diphosphooligosaccharide protein glycosyltransferase subunit 1

E2RQ08

RPN1

8.10

2.5

1/1

68.58

Dystrophin

P11532

DMD

6.02

0.3

1/1

426.74

Elongation factor 1-delta

Q717R8

EEF1D

6.59

3.2

1/1

30.82

Elongation factor 1-gamma (Fragment)

Q29387

EEF1G

26.42

3.0

1/1

49.62

Eukaryotic initiation factor 4A-I (Fragment)

P29562

EIF4A1

10.27

2.5

1/1

45.29

Filamin-B

Q80X90

FLNB

6.91

0.4

1/1

277.82

Fructose-bisphosphate aldolase A

Q5NVR5

ALDOA

14.37

11.5

2/2

39.45

Heterogeneous nuclear ribonucleoprotein C

G3V9R8

HNRNPC

6.05

3.7

1/1

32.86

Heterogeneous nuclear ribonucleoprotein D0

Q60668

HNRNPD

13.29

5.1

2/2

38.35

Heterogeneous nuclear ribonucleoprotein H

Q8VHV7

HNRNPH1

20.84

3.8

1/1

49.19

Heterogeneous nuclear ribonucleoprotein K

P61980

HNRNPK

25.88

4.3

2/2

50.98

Histone H2A type 1-D

C0HKE3

H2AC7

15.46

21.5

2/2

14.14

Ig gamma-1 chain C region secreted form

P01868

IGHG1

106.40

27.5

7/7

35.70

Integrin-linked kinase-associated serine/threonine phosphatase 2C

Q0IIF0

ILKAP

17.46

7.8

3/3

40.62

Interferon-induced very large GTPase 1

Q80SU7

GVIN1

6.44

0.4

1/1

280.81

Interleukin enhancer-binding factor 2

Q9CXY6

ILF2

14.77

6.2

2/2

43.06

Myosin-11 (Fragment)

Q63862

MYH11

93.09

1.2

1/1

152.49

Olfactory receptor 143

P34985

OLFR143

6.31

2.9

1/1

35.20

Poly(rC)-binding protein 2

Q61990

PCBP2

7.13

3.6

1/1

38.22

Prohibitin-2

Q99623

PHB2

8.03

3.3

1/1

33.30

Prostaglandin reductase 1

Q9EQZ5

PTGR1

6.56

3.0

1/1

35.73

Protein disulfide-isomerase

P07237

P4HB

6.48

5.9

1/1

57.12

Protein disulfide-isomerase A3

Q5RDG4

PDIA3

20.51

2.2

1/1

56.78

Protein S100 − A7

P31151

S100A7

105.09

47.5

6/6

11.47

Protein S100−A8

P05109

S100A8

99.03

31.2

3/3

10.83

Protein S100−A9

P06702

S100A9

124.31

51.8

6/6

13.24

Purine nucl−oside phosphorylase

P85973

PNP

6.34

3.5

1/1

32.30

Putative deoxyribonuclease TATDN2

Q93075

TATDN2

6.02

1.2

1/1

85.02

Putative heat shock protein HSP 90-beta 2

Q58FF8

HSP90AB2P

13.40

7.1

1/2

44.35

Pyruvate kinase PKM

P11980

PKM

9.32

4.3

1/1

57.82

RabGDP dissociation inhibitor beta

Q6Q7J2

GDI2

6.77

2.5

1/1

50.27

Ras-related protein Rab-11A

Q5R9M7

RAB11A

10.52

6.0

1/1

24.39

Ras-related protein Rab-6A

Q9WVB1

RAB6A

14.24

5.3

1/1

23.59

RNA binding motif protein, X-linked-like-1

Q91VM5

RBMXL1

10.20

3.4

1/1

42.16

RNA-binding protein EWS

Q61545

EWSR1

14.89

2.1

1/1

68.46

Semenogelin-1

P04279

SEMG1

21.73

7.4

3/3

52.13

Semenogelin-2

Q02383

SEMG2

109.43

7.2

2/2

65.44

Serpin B12

Q96P63

SERPINB12

6.32

2.0

1/1

46.28

Serpin B3

P29508

SERPINB3

26.25

9.2

3/3

44.56

Small proline-rich protein 2D

P22532

SPRR2D

6.14

61.1

1/4

7.91

Small proline-rich protein 2E

P22531

SPRR2E

36.24

79.2

1/4

7.86

Spectrin beta chain, non-erythrocytic 1

Q62261

SPTBN1

6.62

0.4

1/1

274.22

SWI/SNF complex subunit SMARCC2

Q6PDG5

SMARCC2

31.10

2.7

2/2

132.60

T-complex protein 1 subunit gamma

Q6P502

CCT3

15.91

4.0

2/2

60.65

Transcription activator BRG1

A7Z019

SMARCA4

16.83

1.5

2/2

180.68

Transferrin receptor protein 1

Q99376

TFRC

6.19

1.2

1/1

85.88

Transitional endoplasmic reticulum ATPase

Q3ZBT1

VCP

9.18

1.6

1/1

89.33

Tubulin alpha-1B chain

Q4R538

TUBA1B

149.28

18.0

6/6

50.15

Tubulin beta chain

P07437

TUBB

19.24

25.9

1/10

49.67

Tubulin beta-2B chain

Q9CWF2

TUBB2B

8.52

19.8

1/8

49.95

Tubulin beta-4B chain

Q6P9T8

TUBB4B

145.71

29.7

2/11

49.80

Ubiquitin thioesterase OTUB2

Q96DC9

OTUB2

9.63

3.0

1/1

27.21

Voltage-dependent anion-selective channel protein 1

Q9Z2L0

VDAC1

19.45

3.5

1/1

30.76

  1. %Cov = percentage of sequence coverage
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Journal of Translational Medicine

ISSN: 1479-5876

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