Fig. 2From: Gentulizumab, a novel anti-CD47 antibody with potent antitumor activity and demonstrates a favorable safety profileGenSci059 promoted macrophage-mediated phagocytosis of tumor cells in vitro. A Representative images after mouse macrophages were cocultured with Raji cell for 2 h in the presence of 20 μg/ml GenSci059, Hu5F9-G4 or control human IgG4. Tumor cells and macrophages were stained CFSE (green) and PKH-26 (red), respectively; Macrophage-mediated phagocytosis of human B-cell malignancies Raji (B) and Nalm-6 (C). Percentage phagocytosis was quantified by flow cytometry analysesBack to article page