Table 2 Mutations with exceptional high allele frequency
ID | Gender/Age | Location | Stage | Metastasis | DNA | Protein | dbSNP | AF (%) |
|---|---|---|---|---|---|---|---|---|
C004 | M/73 | Sigmoid | IV (cT4N2M1) | Liver | chr18:48591904 C > T | SMAD4 p.P356L |  | 11.61 |
C025 | M/69 | Sigmoid | IV (pT4N2bM1) | Peritoneal cavity | chr17:7577548 C > T | TP53 p.G245S | rs28934575 | 52.92 |
C025 | M/69 | Sigmoid | IV (pT4N2bM1) | Peritoneal cavity | chr12:25398284 C > G | KRAS p.G12A | rs121913529 | 34.94 |
C031 | F/55 | Rectum | IV (pT4aN0M1) | Lung | chr12:25398284 C > G | KRAS p.G12R | rs121913529 | 12.38 |
C040 | M/68 | Sigmoid-Rectum | IV (cT4aNxM1) | Lung | chr17:7578406 C > T | TP53 p.R175H | rs28934578 | 56.86 |
C048 | M/52 | Sigmoid | IV (cTxNxM1) | Liver | chr12:25398284 C > G | KRAS p.G12R | rs121913529 | 11.37 |
C065 | F/75 | Rectum | I (pT1NxM0) |  | chr12:25398284 C > T | KRAS p.G12S | rs121913529 | 21.37 |
C088 | M/60 | Sigmoid-Rectum | IV (cTxNxM1) | Liver | chr17:7577539 G > A | TP53 p.R248W | rs121912651 | 83.42 |